Browsing by Subject "copy number variation"
Now showing items 1-4 of 4
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Article
CNVs-microRNAs interactions demonstrate unique characteristics in the human genome. An interspecies in silico analysis
(2013)MicroRNAs (miRNAs) and copy number variations (CNVs) represent two classes of newly discovered genomic elements that were shown to contribute to genome plasticity and evolution. Recent studies demonstrated that miRNAs and ...
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Article
Increased number of MicroRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction
(2011)MicroRNAs (miRNAs) and copy number variations (CNVs) are two newly discovered genetic elements that have revolutionized the field of molecular biology and genetics. By performing in silico whole genome analysis, we demonstrate ...
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Article
MeDIP real-time qPCR of maternal peripheral blood reliably identifies trisomy 21
(2012)Objective: To reevaluate the efficiency of the 12 differentially methylated regions (DMRs) used in the methylated DNA immunoprecipitation (MeDIP) real-time quantitative polymerase chain reaction (real-time qPCR) based ...
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Article
A new non-invasive prenatal diagnosis of Down syndrome through epigenetic markers and real-time qPCR
(2012)Introduction: Non-invasive prenatal diagnosis (NIPD) of Down syndrome is rapidly evolving. Currently, two applications for NIPD of Down syndrome have been developed with potential and have displayed positive results